Recurrent miscarriage affects about 1-2% of couples trying to conceive. The causes can be diverse, including genetic, anatomical, hormonal, immunological, and lifestyle factors. Common causes include:

• Genetic Factors: Chromosomal abnormalities in the embryo, often due to issues in the parents’ genetic material, can lead to miscarriage.
• Anatomical Abnormalities: Uterine abnormalities, such as septate uterus or fibroids, can interfere with the implantation and growth of the embryo.
• Hormonal Imbalances: Conditions like thyroid dysfunction or polycystic ovary syndrome (PCOS) can affect hormone levels necessary for maintaining a pregnancy.
• Immunological Factors: Autoimmune disorders, where the body’s immune system attacks the embryo, can result in miscarriage.
• Blood Clotting Disorders: Thrombophilia or antiphospholipid syndrome can cause blood clots that impair blood flow to the placenta, leading to miscarriage.

Diagnosis:

At ALGA, we employ a thorough and personalized approach to diagnosing the causes of recurrent miscarriage. This may include:

• Medical History and Physical Examination: A comprehensive review of your medical history and a physical exam to identify any potential risk factors.
• Genetic Testing: Karyotyping of both parents to detect chromosomal abnormalities and genetic testing of the miscarriage tissue, if available.
• Imaging Tests: Ultrasound, hysteroscopy, or MRI to assess the structure of the uterus and detect any anatomical abnormalities.
• Hormonal Assessments: Blood tests to measure hormone levels, including thyroid function and ovarian reserve.
• Immune System Evaluation: Tests to detect autoimmune disorders and blood clotting issues.

Treatment Options:

Based on the findings from the diagnostic evaluations, we develop a personalized treatment plan tailored to your specific needs. Treatment options may include:

1. Genetic Counseling and Testing: If genetic factors are identified, genetic counseling can provide insight and guide future reproductive decisions. Preimplantation genetic testing (PGT) during IVF can help select healthy embryos for transfer.

2. Surgical Interventions: Surgical procedures, such as hysteroscopic resection of uterine septum or fibroids, can correct anatomical abnormalities that contribute to recurrent miscarriage.

3. Hormonal Treatments: Hormonal imbalances can be managed with medications such as thyroid hormone replacement or treatments for PCOS to support a healthy pregnancy.

4. Immunological Therapies: If autoimmune factors are identified, treatments like low-dose aspirin, heparin, or immunotherapy may be recommended to improve pregnancy outcomes.

5. Lifestyle Modifications: Guidance on healthy lifestyle changes, such as maintaining a balanced diet, managing stress, and avoiding harmful substances, can enhance overall reproductive health.